THE EFFECT OF ROBUSTA COFFEE CONSUMPTION ON THE INCIDENT OF LOWER URINARY TRACT SYMPTOMS (LUTS) IN HEALTHY UNDERGRADUATE
##plugins.themes.bootstrap3.article.main##
##plugins.themes.bootstrap3.article.sidebar##
Abstract
Introduction: Lower urinary tract symptoms (LUTS) are common and may impair quality of life. Coffee consumption has been associated with LUTS, although evidence remains inconsistent. Objective: This study aimed to evaluate the effect of robusta coffee consumption on LUTS. Material & Methods: A quasi-experimental design was conducted with 20 medical students. The participants consumed robusta coffee once daily for 14 days as an intervention. LUTS were assessed before and after the intervention using the LURN SI-10 questionnaire, covering storage, voiding, and post-micturition symptom. Results: All 20 participants completed the study. Significant aggravation was observed in urinary urgency (P= 0.035) and nocturia (P= 0.046) after the intervention. However, no significant changes were noted in urinary frequency, incontinence, bladder pain, hesitancy, weak stream, and post-micturition dribble (P> 0.05). Conclusion: Robusta coffee consumption significantly aggravates urinary urgency and nocturia. Keywords: LUTS, robusta coffee, healthy undergraduate.
##plugins.themes.bootstrap3.article.details##
LUTS, robusta coffee, healthy undergraduate
Cella D, Smith AR, Griffith JW, Kirkali Z, Flynn KE, Bradley CS, et al. A New Brief Clinical Assessment of Lower Urinary Tract Symptoms for Women and Men: LURN SI-10. Journal of Urology. 2020 Jan 1;203(1):164–70.
Maserejian NN, Wager CG, Giovannucci EL, Curto TM, McVary KT, McKinlay JB. Intake of Caffeinated, Carbonated, or Citrus Beverage Types and Development of Lower Urinary Tract Symptoms in Men and Women. Am J Epidemiol. 2013 Jun 15;177(12):1399–410.
Tang F, Zhang J, Huang R, Zhou H, Yan T, Tang Z, et al. The association between wet overactive bladder and consumption of tea, coffee, and caffeine: Results from 2005–2018 National Health and Nutrition Examination Survey. Clinical Nutrition. 2024 Jun 1;43(6):1261–9.
Majumdar A. Effects of caffeine on students and caffeinated beverages [Internet]. 2023. Available from: https://www.isarconference.org/
Lohsiriwat S, Hirunsai M, Chaiyaprasithi B. Effect of caffeine on bladder function in patients with overactive bladder symptoms. Urol Ann. 2011 Jan;3(1):14–8.
Cho YS, Ko IG, Kim SE, Hwan L, Shin MS, Kim CJ, et al. Caffeine enhances micturition through neuronal activation in micturition centers. Mol Med Rep. 2014 Dec 1;10(6):2931–6.
Wells MJ, Jamieson K, Markham TCW, Green SM, Fader MJ. The effect of caffeinated versus decaffeinated drinks on overactive bladder. Journal of Wound, Ostomy and Continence Nursing. 2014;41(4):371–8.
Kitta T, Chancellor MB, De Groat WC, Kuno S, Nonomura K, Yoshimura N. Roles of adenosine A1 and A2A receptors in the control of micturition in rats. Neurourol Urodyn. 2014 Nov 1;33(8):1259–65.
Hocher B. Adenosine A1 receptor antagonists in clinical research and development. Kidney Int. 2010 Sep;78(5):438–45.
Kuo IY, Ehrlich BE. Signaling in Muscle Contraction. Cold Spring Harb Perspect Biol. 2015 Feb 2;7(2):a006023.
Guieu R, Degioanni C, Fromonot J, De Maria L, Ruf J, Deharo J, et al. Adenosine, Adenosine Receptors and Neurohumoral Syncope: From Molecular Basis to Personalized Treatment. Biomedicines. 2022 May 13;10(5):1127.
Jagtap S, Harikumar S, Vinayagamoorthy V, Mukhopadhyay S, Dongre A. Comprehensive assessment of holding urine as a behavioral risk factor for UTI in women and reasons for delayed voiding. BMC Infect Dis. 2022 Dec 6;22(1):521.
Reddy VS, Shiva S, Manikantan S, Ramakrishna S. Pharmacology of caffeine and its effects on the human body. Vol. 10, European Journal of Medicinal Chemistry Reports. Elsevier Masson s.r.l.; 2024.
Davis NJ, Vaughan CP, Johnson TM, Goode PS, Burgio KL, Redden DT, et al. Caffeine Intake and its Association with Urinary Incontinence in United States Men: Results from National Health and Nutrition Examination Surveys 2005–2006 and 2007–2008. Journal of Urology. 2013 Jun;189(6):2170–4.
Jura YH, Townsend MK, Curhan GC, Resnick NM, Grodstein F. Caffeine Intake, and the Risk of Stress, Urgency and Mixed Urinary Incontinence. Journal of Urology. 2011 May;185(5):1775–80.
Yeh CH, Praveen Rajneesh C, Liao CH, You WC, Chen KC, Wu YN, et al. Chlorogenic Acid Intravesical Therapy Changes Acute Voiding Behavior of Systemic Lipopolysaccharide Inflammation-Induced Cystitis Bladder in Mice. Toxics. 2024 Mar 25;12(4):239.